Sarah Streck

College: Christian-Albrechts University of Kiel, Germany

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Thesis title: Cell penetrating peptides for enhanced oral delivery of nanoformulations

Co-supervisors:

Assoc. Prof. Hanne Mørck Nielsen (Department of Pharmacy, University of Copenhagen, Denmark)

Prof. Thomas Rades (Department of Pharmacy, University of Copenhagen, Denmark)

 

Project description:

The aim of my PhD is to solve the limited ability of drugs to cross the gastrointestinal membrane by using polymeric nanoparticles as a drug delivery system to encapsulate drugs and facilitate their oral absorption. These polymeric nanoparticles will be produced using a microfluidic approach. Further, the surface of the nanoparticles will be modified with cell penetrating peptides (CPPs) to enhance cellular uptake.