{"id":523,"date":"2015-09-06T09:16:53","date_gmt":"2015-09-05T21:16:53","guid":{"rendered":"http:\/\/arlenemcdowell.com\/wordpress\/?page_id=523"},"modified":"2016-06-30T16:41:24","modified_gmt":"2016-06-30T04:41:24","slug":"isabella-hold","status":"publish","type":"page","link":"http:\/\/arlenemcdowell.com\/wordpress\/group-members\/postgraduate-certificate-and-visiting-students\/isabella-hold\/","title":{"rendered":"Isabella Hold"},"content":{"rendered":"<p><a href=\"http:\/\/arlenemcdowell.com\/wordpress\/wp-content\/uploads\/2015\/09\/webpage_photo_isabella.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-medium wp-image-524\" src=\"http:\/\/arlenemcdowell.com\/wordpress\/wp-content\/uploads\/2015\/09\/webpage_photo_isabella-300x169.jpg\" alt=\"webpage_photo_isabella\" width=\"300\" height=\"169\" srcset=\"http:\/\/arlenemcdowell.com\/wordpress\/wp-content\/uploads\/2015\/09\/webpage_photo_isabella-300x169.jpg 300w, http:\/\/arlenemcdowell.com\/wordpress\/wp-content\/uploads\/2015\/09\/webpage_photo_isabella-1024x576.jpg 1024w, http:\/\/arlenemcdowell.com\/wordpress\/wp-content\/uploads\/2015\/09\/webpage_photo_isabella-500x281.jpg 500w, http:\/\/arlenemcdowell.com\/wordpress\/wp-content\/uploads\/2015\/09\/webpage_photo_isabella.jpg 1056w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p>&nbsp;<\/p>\n<p><strong>College:<\/strong>\u00a0Karl-Franzens University Graz, Austria<\/p>\n<p><strong>Email:\u00a0: <\/strong><a href=\"mailto:Isabella.hold@edu.uni-graz.at\">Isabella.hold@edu.uni-graz.at<\/a><\/p>\n<p>&nbsp;<\/p>\n<p>Prof. Andreas Zimmer (Institute of Pharmaceutical Technology, Karl-Franzens University of Graz) was the thesis supervisor of this project.<\/p>\n<p>Dr Julia Horsfield (Otago Zebrafish Facility, University of Otago) was a key collaborator in this project.<\/p>\n<p><strong>Project title: \u00a0<\/strong><em>In vivo<\/em> response to antioxidant\u00a0nanomedicines using a zebrafish model<\/p>\n<p style=\"text-align: justify;\"><strong>Project description:\u00a0<\/strong>The consumption of plant-derived antioxidants has been associated with the prevention of diseases, including cancer and neurodegenerative disorders, caused by oxidative stress.\u00a0 Leaves of the puha plant (<em>Sonchus oleraceus<\/em>) are rich in antioxidants that have the potential to be formulated into a supplement product. We have previously shown that <em>S. oleraceus<\/em> antioxidants are absorbed into cells <em>in vitro<\/em> and can exert an antioxidant effect.\u00a0 Can this effect be maintained following <em>in vivo <\/em>administration?\u00a0 Delivery of antioxidants using nanoparticle formulations will be investigated <em>in vivo<\/em> using zebrafish embryos, an exciting new model of human disease in which to study oxidative stress.<\/p>\n<p><strong>Aim<\/strong>: To investigate the <em>in vivo<\/em> response to administration of antioxidants in nanoparticles using a zebrafish model<\/p>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; College:\u00a0Karl-Franzens University Graz, Austria Email:\u00a0: Isabella.hold@edu.uni-graz.at &nbsp; Prof. Andreas Zimmer (Institute of Pharmaceutical Technology, Karl-Franzens University of Graz) was the thesis supervisor of this project. Dr Julia Horsfield (Otago Zebrafish Facility, University of Otago) was a key collaborator in &hellip; <a href=\"http:\/\/arlenemcdowell.com\/wordpress\/group-members\/postgraduate-certificate-and-visiting-students\/isabella-hold\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":118,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"_links":{"self":[{"href":"http:\/\/arlenemcdowell.com\/wordpress\/wp-json\/wp\/v2\/pages\/523"}],"collection":[{"href":"http:\/\/arlenemcdowell.com\/wordpress\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/arlenemcdowell.com\/wordpress\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/arlenemcdowell.com\/wordpress\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/arlenemcdowell.com\/wordpress\/wp-json\/wp\/v2\/comments?post=523"}],"version-history":[{"count":4,"href":"http:\/\/arlenemcdowell.com\/wordpress\/wp-json\/wp\/v2\/pages\/523\/revisions"}],"predecessor-version":[{"id":537,"href":"http:\/\/arlenemcdowell.com\/wordpress\/wp-json\/wp\/v2\/pages\/523\/revisions\/537"}],"up":[{"embeddable":true,"href":"http:\/\/arlenemcdowell.com\/wordpress\/wp-json\/wp\/v2\/pages\/118"}],"wp:attachment":[{"href":"http:\/\/arlenemcdowell.com\/wordpress\/wp-json\/wp\/v2\/media?parent=523"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}