{"id":199,"date":"2015-03-19T16:07:38","date_gmt":"2015-03-19T03:07:38","guid":{"rendered":"http:\/\/arlenemcdowell.com\/wordpress\/?page_id=199"},"modified":"2017-02-01T19:27:31","modified_gmt":"2017-02-01T06:27:31","slug":"birgitte-larsen","status":"publish","type":"page","link":"http:\/\/arlenemcdowell.com\/wordpress\/group-members\/masters-students\/birgitte-larsen\/","title":{"rendered":"Birgitte Larsen"},"content":{"rendered":"<p style=\"text-align: justify;\"><strong><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-200 size-medium\" src=\"http:\/\/arlenemcdowell.com\/wordpress\/wp-content\/uploads\/2015\/03\/me-300x300.jpg\" alt=\"me\" width=\"300\" height=\"300\" srcset=\"http:\/\/arlenemcdowell.com\/wordpress\/wp-content\/uploads\/2015\/03\/me-300x300.jpg 300w, http:\/\/arlenemcdowell.com\/wordpress\/wp-content\/uploads\/2015\/03\/me-150x150.jpg 150w, http:\/\/arlenemcdowell.com\/wordpress\/wp-content\/uploads\/2015\/03\/me.jpg 960w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/>College: \u00a0<\/strong>University of Copenhagen, Denmark<\/p>\n<p><strong>Email:<\/strong> gxz868@alumni.ku.dk<\/p>\n<p style=\"text-align: justify;\"><strong>Thesis title:<\/strong> Investigation of the pharmacokinetics of aniracetam and its metabolite N-anisoyl-GABA in pigeons<\/p>\n<p><strong>Co-supervisor:<\/strong> Dr Lene\u00a0<span class=\"Apple-style-span\">J\u00f8rgensen (University of Copenhagen, Denmark)<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><strong>Project description:<\/strong><\/p>\n<p style=\"text-align: justify;\">There is an increasing need to develop drugs that can improve cognitive decline.\u00a0 Aniracetam is a nootropic drug that has potential cognition-enhancing effects and is being investigated as a treatment for Alzheimer\u2019s disease.\u00a0 In humans, aniracetam is rapidly absorbed from the gastrointestinal tract and the majority of the drug is rapidly metabolized to the active metabolite, N-anisoyl-GABA.<\/p>\n<p class=\"Default\" style=\"text-align: justify;\"><span lang=\"EN-GB\"><span style=\"font-size: medium;\">The enhanced memory effect of aniracetam is being investigated in avian species because birds can be trained to perform a wider range of learning and memory tasks than traditional laboratory species such as rats.\u00a0 Further, birds have the glutamate receptors that are modulated in humans by aniracetam.\u00a0 However, the pharmacokinetics of aniracetam in birds is currently unknown.<\/span><\/span><\/p>\n<p class=\"Default\" style=\"text-align: justify;\"><span lang=\"EN-GB\">To\u00a0investigate the pharmacokinetics of aniracetam I will use HPLC and LC-MS\/MS. \u00a0<\/span><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>College: \u00a0University of Copenhagen, Denmark Email: gxz868@alumni.ku.dk Thesis title: Investigation of the pharmacokinetics of aniracetam and its metabolite N-anisoyl-GABA in pigeons Co-supervisor: Dr Lene\u00a0J\u00f8rgensen (University of Copenhagen, Denmark) &nbsp; Project description: There is an increasing need to develop drugs that &hellip; <a href=\"http:\/\/arlenemcdowell.com\/wordpress\/group-members\/masters-students\/birgitte-larsen\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":262,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"_links":{"self":[{"href":"http:\/\/arlenemcdowell.com\/wordpress\/wp-json\/wp\/v2\/pages\/199"}],"collection":[{"href":"http:\/\/arlenemcdowell.com\/wordpress\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/arlenemcdowell.com\/wordpress\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/arlenemcdowell.com\/wordpress\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/arlenemcdowell.com\/wordpress\/wp-json\/wp\/v2\/comments?post=199"}],"version-history":[{"count":13,"href":"http:\/\/arlenemcdowell.com\/wordpress\/wp-json\/wp\/v2\/pages\/199\/revisions"}],"predecessor-version":[{"id":625,"href":"http:\/\/arlenemcdowell.com\/wordpress\/wp-json\/wp\/v2\/pages\/199\/revisions\/625"}],"up":[{"embeddable":true,"href":"http:\/\/arlenemcdowell.com\/wordpress\/wp-json\/wp\/v2\/pages\/262"}],"wp:attachment":[{"href":"http:\/\/arlenemcdowell.com\/wordpress\/wp-json\/wp\/v2\/media?parent=199"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}