{"id":1045,"date":"2018-11-15T14:37:55","date_gmt":"2018-11-15T01:37:55","guid":{"rendered":"http:\/\/arlenemcdowell.com\/wordpress\/?page_id=1045"},"modified":"2018-11-17T18:09:08","modified_gmt":"2018-11-17T05:09:08","slug":"alisa-goutach","status":"publish","type":"page","link":"http:\/\/arlenemcdowell.com\/wordpress\/group-members\/postgraduate-certificate-and-visiting-students\/alisa-goutach\/","title":{"rendered":"Alisa Goutach"},"content":{"rendered":"<p style=\"text-align: justify;\"><strong><a href=\"http:\/\/arlenemcdowell.com\/wordpress\/wp-content\/uploads\/2018\/11\/4105e200-dc8f-4cf1-91db-03b7581ef5f1-2.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-medium wp-image-1046\" src=\"http:\/\/arlenemcdowell.com\/wordpress\/wp-content\/uploads\/2018\/11\/4105e200-dc8f-4cf1-91db-03b7581ef5f1-2-268x300.jpg\" alt=\"\" width=\"268\" height=\"300\" srcset=\"http:\/\/arlenemcdowell.com\/wordpress\/wp-content\/uploads\/2018\/11\/4105e200-dc8f-4cf1-91db-03b7581ef5f1-2-268x300.jpg 268w, http:\/\/arlenemcdowell.com\/wordpress\/wp-content\/uploads\/2018\/11\/4105e200-dc8f-4cf1-91db-03b7581ef5f1-2.jpg 618w\" sizes=\"(max-width: 268px) 100vw, 268px\" \/><\/a>College:\u00a0<\/strong>Johann Wolfgang Goethe University of Frankfurt, Germany<\/p>\n<p><strong>Email:<\/strong> a.goutach@gmail.com<\/p>\n<p><strong>Co-supervisor:<\/strong>\u00a0Sarah Streck<\/p>\n<p><strong>Project title: <\/strong>Uptake\u00a0of nanoparticles decorated with cell penetrating peptides<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Project description:<\/strong><\/p>\n<p>Nanoparticle drug carriers decorated with cell penetrating peptides is an elegant and modern formulation approach to improve drug delivery. However, the uptake mechanisms at human biomembranes is not well understood. Is there a difference in cellular uptake of cell penetrating peptides with different molecular architecture? Using microfluidics techniques to produce nanoparticles of uniform size is a suitable tool to understand structural differences on the surface of nanoparticles due to decoration with cell penetrating peptides.<\/p>\n<p>The main aim of this project is to gain understanding of cellular and molecular uptake mechanisms of cell penetrating peptide decorated PLGA-nanoparticles using\u00a0<em>in vitro <\/em>models like CaCo-2 cells.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>College:\u00a0Johann Wolfgang Goethe University of Frankfurt, Germany Email: a.goutach@gmail.com Co-supervisor:\u00a0Sarah Streck Project title: Uptake\u00a0of nanoparticles decorated with cell penetrating peptides &nbsp; &nbsp; &nbsp; Project description: Nanoparticle drug carriers decorated with cell penetrating peptides is an elegant and modern formulation approach &hellip; <a href=\"http:\/\/arlenemcdowell.com\/wordpress\/group-members\/postgraduate-certificate-and-visiting-students\/alisa-goutach\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":118,"menu_order":1,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"_links":{"self":[{"href":"http:\/\/arlenemcdowell.com\/wordpress\/wp-json\/wp\/v2\/pages\/1045"}],"collection":[{"href":"http:\/\/arlenemcdowell.com\/wordpress\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/arlenemcdowell.com\/wordpress\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/arlenemcdowell.com\/wordpress\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/arlenemcdowell.com\/wordpress\/wp-json\/wp\/v2\/comments?post=1045"}],"version-history":[{"count":5,"href":"http:\/\/arlenemcdowell.com\/wordpress\/wp-json\/wp\/v2\/pages\/1045\/revisions"}],"predecessor-version":[{"id":1056,"href":"http:\/\/arlenemcdowell.com\/wordpress\/wp-json\/wp\/v2\/pages\/1045\/revisions\/1056"}],"up":[{"embeddable":true,"href":"http:\/\/arlenemcdowell.com\/wordpress\/wp-json\/wp\/v2\/pages\/118"}],"wp:attachment":[{"href":"http:\/\/arlenemcdowell.com\/wordpress\/wp-json\/wp\/v2\/media?parent=1045"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}